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Cytomegalovirus Exposure in the Elderly Does Not Reduce CD8 T Cell Repertoire Diversity

With age, the immune system becomes less effective, causing increased susceptibility to infection. Chronic CMV infection further impairs immune function and is associated with increased mortality in the elderly. CMV exposure elicits massive CD8(+) T cell clonal expansions and diminishes the cytotoxi...

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Detalles Bibliográficos
Autores principales:	Lindau, Paul, Mukherjee, Rithun, Gutschow, Miriam V., Vignali, Marissa, Warren, Edus H., Riddell, Stanley R., Makar, Karen W., Turtle, Cameron J., Robins, Harlan S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2019
Materias:	Infectious Disease and Host Response
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321841/ https://www.ncbi.nlm.nih.gov/pubmed/30541882 http://dx.doi.org/10.4049/jimmunol.1800217

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