A Randomized, Placebo-controlled Trial of Fidaxomicin for Prophylaxis of Clostridium difficile–associated Diarrhea in Adults Undergoing Hematopoietic Stem Cell Transplantation

BACKGROUND: Clostridium difficile–associated diarrhea (CDAD) is common during hematopoietic stem-cell transplantation (HSCT) and is associated with increased morbidity and mortality. We evaluated fidaxomicin for prevention of CDAD in HSCT patients. METHODS: In this double-blind study, subjects under...

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Detalles Bibliográficos
Autores principales: Mullane, Kathleen M, Winston, Drew J, Nooka, Ajay, Morris, Michele I, Stiff, Patrick, Dugan, Michael J, Holland, Henry, Gregg, Kevin, Adachi, Javier A, Pergam, Steven A, Alexander, Barbara D, Dubberke, Erik R, Broyde, Natalya, Gorbach, Sherwood L, Sears, Pamela S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Articles and Commentaries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321849/
https://www.ncbi.nlm.nih.gov/pubmed/29893798
http://dx.doi.org/10.1093/cid/ciy484

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