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Determining the Mutation Bias of Favipiravir in Influenza Virus Using Next-Generation Sequencing

Favipiravir is a broad-spectrum antiviral drug that may be used to treat influenza. Previous research has identified that favipiravir likely acts as a mutagen, but the precise mutation bias that favipiravir induces in influenza virus RNAs has not been described. Here, we use next-generation sequenci...

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Detalles Bibliográficos
Autores principales:	Goldhill, Daniel H., Langat, Pinky, Xie, Hongyao, Galiano, Monica, Miah, Shahjahan, Kellam, Paul, Zambon, Maria, Lackenby, Angie, Barclay, Wendy S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Vaccines and Antiviral Agents
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321902/ https://www.ncbi.nlm.nih.gov/pubmed/30381482 http://dx.doi.org/10.1128/JVI.01217-18

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