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Metagenomic Sequencing of HIV-1 in the Blood and Female Genital Tract Reveals Little Quasispecies Diversity during Acute Infection

Heterosexual transmission of human immunodeficiency virus type 1 (HIV-1) is associated with a significant bottleneck in the viral quasispecies population, yet the timing of that bottleneck is poorly understood. We characterized HIV-1 diversity in the blood and female genital tract (FGT) within 2 wee...

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Detalles Bibliográficos
Autores principales:	Piantadosi, Anne, Freije, Catherine A., Gosmann, Christina, Ye, Simon, Park, Daniel, Schaffner, Stephen F., Tully, Damien C., Allen, Todd M., Dong, Krista L., Sabeti, Pardis C., Kwon, Douglas S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2019
Materias:	Genetic Diversity and Evolution
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6321908/ https://www.ncbi.nlm.nih.gov/pubmed/30381486 http://dx.doi.org/10.1128/JVI.00804-18

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