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A unique case of hemi-tongue pseudohypertrophy, necrotizing myopathy, and erythema nodosum

A 46-year-old woman developed slowly progressive tongue weakness with a pseudohypertrophic change on the right side of her tongue. She subsequently developed weakness in her proximal lower extremities, skin erythema and a sustained increase of muscle enzymes at 11 M after the onset. A biopsy of the...

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Detalles Bibliográficos
Autores principales: Sato, Kota, Takahashi, Yoshiaki, Yamashita, Toru, Takemoto, Mami, Hishikawa, Nozomi, Jinwei, Shang, Ohta, Yasuyuki, Abe, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PAGEPress Publications, Pavia, Italy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322047/
https://www.ncbi.nlm.nih.gov/pubmed/30687466
http://dx.doi.org/10.4081/ni.2018.7852
Descripción
Sumario:A 46-year-old woman developed slowly progressive tongue weakness with a pseudohypertrophic change on the right side of her tongue. She subsequently developed weakness in her proximal lower extremities, skin erythema and a sustained increase of muscle enzymes at 11 M after the onset. A biopsy of the quadriceps muscle showed necrotizing myopathy and a skin biopsy showed erythema nodosum. The present case showed characteristic clinical manifestations that may represent a rare variant of sarcoidosis.