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Urodynamic Changes after Valve Fulguration Alone and Valve Fulguration with Bladder Neck Incision

AIMS: The aim of this study is to compare urodynamic changes after valve fulguration alone and valve fulguration with bladder neck incision (BNI). SETTINGS AND DESIGN: A total of 81 patients with posterior urethral valve were treated at our center from July 2010 to July 2016. Patients were randomize...

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Autores principales: Singh, Sanjeet Kumar, Sharma, Vijay, Singh, Anjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322172/
https://www.ncbi.nlm.nih.gov/pubmed/30686885
http://dx.doi.org/10.4103/jiaps.JIAPS_141_17
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author Singh, Sanjeet Kumar
Sharma, Vijay
Singh, Anjana
author_facet Singh, Sanjeet Kumar
Sharma, Vijay
Singh, Anjana
author_sort Singh, Sanjeet Kumar
collection PubMed
description AIMS: The aim of this study is to compare urodynamic changes after valve fulguration alone and valve fulguration with bladder neck incision (BNI). SETTINGS AND DESIGN: A total of 81 patients with posterior urethral valve were treated at our center from July 2010 to July 2016. Patients were randomized into two groups using simple randomization. Forty patients underwent BNI in addition to valve fulguration (Group I), and the remaining 41 patients underwent conventional transurethral valve fulguration (Group II). SUBJECTS AND METHODS: The exclusion criteria for both the groups were the presence of simultaneous urogenital anomalies, any neurological condition, history of any urethral manipulation, and urinary diversion. Urodynamic changes were compared in both groups postoperatively. All patients were evaluated throughout their follow-up, according to the following protocol: (a) Voiding cystourethrography at 6 weeks after surgery; (b) Renal function test and urine culture at 6 weeks and then 3 monthly; (c) Ultrasound kidney, ureter, and bladder region and urodynamics at 3 and 6 months after surgery and then yearly. Median follow-up period for Group I was 27.5 months (13–72 months) and 14 months (14.5–72 months) for Group II. STATISTICAL ANALYSIS USED: Statistical analysis was done using the Student's t-test for parametric data and Chi-square test for categorical variable. P ≤ 0.05 was considered as statistically significant. RESULTS: The mean age was 7.26 years in Group I and 7.66 years in Group II at the end of follow-up. There was no statistically significant difference found regarding detrusor overactivity (P = 0.68), compliance (P = 0.052), end-filling pressure (P = 0.08), and max Pdet at Q(max) (P = 0.08) in the both groups. However, there was a statistically significant difference regarding improvement of peak flow (P = 0.038) and postvoid residue (PVR) (P = 0.045) in Group I in comparison to Group II. CONCLUSIONS: Valve ablation with BNI gives statistically significant better urodynamics in voiding phase regarding flow and lesser PVR in comparison to valve ablation.
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spelling pubmed-63221722019-01-25 Urodynamic Changes after Valve Fulguration Alone and Valve Fulguration with Bladder Neck Incision Singh, Sanjeet Kumar Sharma, Vijay Singh, Anjana J Indian Assoc Pediatr Surg Original Article AIMS: The aim of this study is to compare urodynamic changes after valve fulguration alone and valve fulguration with bladder neck incision (BNI). SETTINGS AND DESIGN: A total of 81 patients with posterior urethral valve were treated at our center from July 2010 to July 2016. Patients were randomized into two groups using simple randomization. Forty patients underwent BNI in addition to valve fulguration (Group I), and the remaining 41 patients underwent conventional transurethral valve fulguration (Group II). SUBJECTS AND METHODS: The exclusion criteria for both the groups were the presence of simultaneous urogenital anomalies, any neurological condition, history of any urethral manipulation, and urinary diversion. Urodynamic changes were compared in both groups postoperatively. All patients were evaluated throughout their follow-up, according to the following protocol: (a) Voiding cystourethrography at 6 weeks after surgery; (b) Renal function test and urine culture at 6 weeks and then 3 monthly; (c) Ultrasound kidney, ureter, and bladder region and urodynamics at 3 and 6 months after surgery and then yearly. Median follow-up period for Group I was 27.5 months (13–72 months) and 14 months (14.5–72 months) for Group II. STATISTICAL ANALYSIS USED: Statistical analysis was done using the Student's t-test for parametric data and Chi-square test for categorical variable. P ≤ 0.05 was considered as statistically significant. RESULTS: The mean age was 7.26 years in Group I and 7.66 years in Group II at the end of follow-up. There was no statistically significant difference found regarding detrusor overactivity (P = 0.68), compliance (P = 0.052), end-filling pressure (P = 0.08), and max Pdet at Q(max) (P = 0.08) in the both groups. However, there was a statistically significant difference regarding improvement of peak flow (P = 0.038) and postvoid residue (PVR) (P = 0.045) in Group I in comparison to Group II. CONCLUSIONS: Valve ablation with BNI gives statistically significant better urodynamics in voiding phase regarding flow and lesser PVR in comparison to valve ablation. Medknow Publications & Media Pvt Ltd 2019 /pmc/articles/PMC6322172/ /pubmed/30686885 http://dx.doi.org/10.4103/jiaps.JIAPS_141_17 Text en Copyright: © 2018 Journal of Indian Association of Pediatric Surgeons http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Singh, Sanjeet Kumar
Sharma, Vijay
Singh, Anjana
Urodynamic Changes after Valve Fulguration Alone and Valve Fulguration with Bladder Neck Incision
title Urodynamic Changes after Valve Fulguration Alone and Valve Fulguration with Bladder Neck Incision
title_full Urodynamic Changes after Valve Fulguration Alone and Valve Fulguration with Bladder Neck Incision
title_fullStr Urodynamic Changes after Valve Fulguration Alone and Valve Fulguration with Bladder Neck Incision
title_full_unstemmed Urodynamic Changes after Valve Fulguration Alone and Valve Fulguration with Bladder Neck Incision
title_short Urodynamic Changes after Valve Fulguration Alone and Valve Fulguration with Bladder Neck Incision
title_sort urodynamic changes after valve fulguration alone and valve fulguration with bladder neck incision
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322172/
https://www.ncbi.nlm.nih.gov/pubmed/30686885
http://dx.doi.org/10.4103/jiaps.JIAPS_141_17
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