Evidence-based sizing of non-inferiority trials using decision models

BACKGROUND: There are significant challenges to the successful conduct of non-inferiority trials because they require large numbers to demonstrate that an alternative intervention is “not too much worse” than the standard. In this paper, we present a novel strategy for designing non-inferiority tria...

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Detalles Bibliográficos
Autores principales: Lansdorp-Vogelaar, Iris, Jagsi, Reshma, Jayasekera, Jinani, Stout, Natasha K., Mitchell, Sandra A., Feuer, Eric J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322228/
https://www.ncbi.nlm.nih.gov/pubmed/30612554
http://dx.doi.org/10.1186/s12874-018-0643-2

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