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Real-time molecular optical micro-imaging of EGFR mutations using a fluorescent erlotinib based tracer

BACKGROUND: EGFR mutations are routinely explored in lung adenocarcinoma by sequencing tumoral DNA. The aim of this study was to evaluate a fluorescent-labelled erlotinib based theranostic agent for the molecular imaging of mutated EGFR tumours in vitro and ex vivo using a mice xenograft model and f...

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Detalles Bibliográficos
Autores principales:	Patout, Maxime, Guisier, Florian, Brune, Xavier, Bohn, Pierre, Romieu, Anthony, Sarafan-Vasseur, Nasrin, Sesboüé, Richard, Renard, Pierre-Yves, Thiberville, Luc, Salaün, Mathieu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322267/ https://www.ncbi.nlm.nih.gov/pubmed/30612556 http://dx.doi.org/10.1186/s12890-018-0760-z

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