Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study

BACKGROUND: In gout, long-term urate-lowering therapy (ULT) promotes dissolution of tissue urate crystal deposits. However, no studies using combined xanthine oxidase inhibition and uricosuric ULT have focused on clinical outcomes or adverse events (AEs) beyond 12 months of therapy. Our objective in...

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Detalles Bibliográficos
Autores principales: Dalbeth, Nicola, Jones, Graeme, Terkeltaub, Robert, Khanna, Dinesh, Fung, Maple, Baumgartner, Scott, Perez-Ruiz, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322285/
https://www.ncbi.nlm.nih.gov/pubmed/30616614
http://dx.doi.org/10.1186/s13075-018-1788-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322285/
https://www.ncbi.nlm.nih.gov/pubmed/30616614
http://dx.doi.org/10.1186/s13075-018-1788-4

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