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Differences in tumor microenvironments between primary lung tumors and brain metastases in lung cancer patients: therapeutic implications for immune checkpoint inhibitors

BACKGROUND: We aimed to compare intra- and extracranial responses to immune checkpoint inhibitors (ICIs) in lung cancer with brain metastases (BM), and to explore tumor microenvironments of the brain and lungs focusing on the programmed cell death-1 (PD-1)/programmed cell death ligand-1 (PD-L1) path...

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Detalles Bibliográficos
Autores principales:	Kim, Ryul, Keam, Bhumsuk, Kim, Sehui, Kim, Miso, Kim, Se Hyun, Kim, Jin Wook, Kim, Yu Jung, Kim, Tae Min, Jeon, Yoon Kyung, Kim, Dong-Wan, Chung, Doo Hyun, Lee, Jong Seok, Heo, Dae Seog
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322302/ https://www.ncbi.nlm.nih.gov/pubmed/30616523 http://dx.doi.org/10.1186/s12885-018-5214-8

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