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Stromal-Interacting Molecule 1 (Stim1)/Orai1 Modulates Endothelial Permeability in Ventilator-Induced Lung Injury

BACKGROUND: Increased endothelial permeability is involved in ventilator-induced lung injury (VILI). Stim1/Orai1 mediates store-operated Ca(2+) activation, which modulates endothelial permeability. However, the underlying mechanisms of the Stim1/Orai1 pathway in VILI are poorly understood. MATERIAL/...

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Detalles Bibliográficos
Autores principales: Song, Xiumei, Liu, Yang, Dong, Ling, Wang, Yuelan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322368/
https://www.ncbi.nlm.nih.gov/pubmed/30589833
http://dx.doi.org/10.12659/MSM.911268