Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival

The tumor microenvironment is fundamental to cancer progression, and the influence of its mechanical properties is increasingly being appreciated. Tamoxifen has been used for many years to treat estrogen‐positive breast cancer. Here we report that tamoxifen regulates the level and activity of collag...

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Detalles Bibliográficos
Autores principales: Cortes, Ernesto, Lachowski, Dariusz, Robinson, Benjamin, Sarper, Muge, Teppo, Jaakko S, Thorpe, Stephen D, Lieberthal, Tyler J, Iwamoto, Kazunari, Lee, David A, Okada‐Hatakeyama, Mariko, Varjosalo, Markku T, del Río Hernández, Armando E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322388/
https://www.ncbi.nlm.nih.gov/pubmed/30538116
http://dx.doi.org/10.15252/embr.201846557

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