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Utility of FineNeedle Aspiration Cytology as a Lowcost Tool to Diagnose Cervical Lymphadenopathy
BACKGROUND AND OBJECTIVE: The current study aimed at observing the cytomorpho logical patterns in patients presenting with enlarged cervical lymphnodes, diagnosed by fine needle aspiration cytology (FNAC), their distribution with respect to age and gender, and determining the accuracy of FNAC as a d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Iranian Society of Pathology
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322528/ https://www.ncbi.nlm.nih.gov/pubmed/30636957 |
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author | Sejwal, Pranjali Jaiswal, Milan Pandey, Surbhi |
author_facet | Sejwal, Pranjali Jaiswal, Milan Pandey, Surbhi |
author_sort | Sejwal, Pranjali |
collection | PubMed |
description | BACKGROUND AND OBJECTIVE: The current study aimed at observing the cytomorpho logical patterns in patients presenting with enlarged cervical lymphnodes, diagnosed by fine needle aspiration cytology (FNAC), their distribution with respect to age and gender, and determining the accuracy of FNAC as a diagnostic procedure in cases with cervical lymphadenopathy. METHODS: Out of all patients presenting with cervical lymphadenopathy from Sep tember 2015 to September 2016, in the Department of Pathology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India 100 consecutive cases were enrolled into the current study, following the exclusion of all cases where FNAC smears were inadequate or suboptimal for diagnostic interpretation. Histopath ological examination was conducted on small excision biopsy specimens/radical neck dissection, where ever possible and diagnostic efficacy of FNAC was evaluated. RESULTS: The overall age range of the enrolled patients, presenting with enlarged cervical lymph nodes, was 172 years with the mean age of 35.7 years and male femaleratio of 1.6:1.Out of the 100 cases, benign and malignant lesions comprised 77 and 23 cases, respectively. The most common observed benign lesion was reactive hyperplasia (29%), while squamous cell carcinoma was the most common malignant lesion.The overall sensitivity, specificity, positive predictive value, negative predic tive value, and the diagnostic accuracy was 100%, 91.67%, 92%, 100%, and 95.7%, respectively. CONCLUSION: FNAC in the diagnoses of inflammatory and neoplastic diseases serves as a reliable,lowcost, rapid diagnostic tool with reasonably good accuracy that can influence patient management in terms of early diagnoses, treatment, and prevention of unnecessary surgery in patients. |
format | Online Article Text |
id | pubmed-6322528 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Iranian Society of Pathology |
record_format | MEDLINE/PubMed |
spelling | pubmed-63225282019-01-11 Utility of FineNeedle Aspiration Cytology as a Lowcost Tool to Diagnose Cervical Lymphadenopathy Sejwal, Pranjali Jaiswal, Milan Pandey, Surbhi Iran J Pathol Original Article BACKGROUND AND OBJECTIVE: The current study aimed at observing the cytomorpho logical patterns in patients presenting with enlarged cervical lymphnodes, diagnosed by fine needle aspiration cytology (FNAC), their distribution with respect to age and gender, and determining the accuracy of FNAC as a diagnostic procedure in cases with cervical lymphadenopathy. METHODS: Out of all patients presenting with cervical lymphadenopathy from Sep tember 2015 to September 2016, in the Department of Pathology, Shri Ram Murti Smarak Institute of Medical Sciences, Bareilly, Uttar Pradesh, India 100 consecutive cases were enrolled into the current study, following the exclusion of all cases where FNAC smears were inadequate or suboptimal for diagnostic interpretation. Histopath ological examination was conducted on small excision biopsy specimens/radical neck dissection, where ever possible and diagnostic efficacy of FNAC was evaluated. RESULTS: The overall age range of the enrolled patients, presenting with enlarged cervical lymph nodes, was 172 years with the mean age of 35.7 years and male femaleratio of 1.6:1.Out of the 100 cases, benign and malignant lesions comprised 77 and 23 cases, respectively. The most common observed benign lesion was reactive hyperplasia (29%), while squamous cell carcinoma was the most common malignant lesion.The overall sensitivity, specificity, positive predictive value, negative predic tive value, and the diagnostic accuracy was 100%, 91.67%, 92%, 100%, and 95.7%, respectively. CONCLUSION: FNAC in the diagnoses of inflammatory and neoplastic diseases serves as a reliable,lowcost, rapid diagnostic tool with reasonably good accuracy that can influence patient management in terms of early diagnoses, treatment, and prevention of unnecessary surgery in patients. Iranian Society of Pathology 2018 2018-09-12 /pmc/articles/PMC6322528/ /pubmed/30636957 Text en © 2018, IRANIAN JOURNAL OF PATHOLOGY. This is an open-access article distributed under the terms of the Creative Commons Attribution-noncommercial 4.0 International License, (https://creativecommons.org/licenses/by-nc/4.0/) which permits copy and redistribute the material just in noncommercial usages, provided the original work is properly cited. |
spellingShingle | Original Article Sejwal, Pranjali Jaiswal, Milan Pandey, Surbhi Utility of FineNeedle Aspiration Cytology as a Lowcost Tool to Diagnose Cervical Lymphadenopathy |
title | Utility of FineNeedle Aspiration Cytology as a Lowcost Tool to Diagnose Cervical Lymphadenopathy |
title_full | Utility of FineNeedle Aspiration Cytology as a Lowcost Tool to Diagnose Cervical Lymphadenopathy |
title_fullStr | Utility of FineNeedle Aspiration Cytology as a Lowcost Tool to Diagnose Cervical Lymphadenopathy |
title_full_unstemmed | Utility of FineNeedle Aspiration Cytology as a Lowcost Tool to Diagnose Cervical Lymphadenopathy |
title_short | Utility of FineNeedle Aspiration Cytology as a Lowcost Tool to Diagnose Cervical Lymphadenopathy |
title_sort | utility of fineneedle aspiration cytology as a lowcost tool to diagnose cervical lymphadenopathy |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322528/ https://www.ncbi.nlm.nih.gov/pubmed/30636957 |
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