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A potent Lassa virus antiviral targets an arenavirus virulence determinant
Arenaviruses are a significant cause of hemorrhagic fever, an often-fatal disease for which there is no approved antiviral therapy. Lassa fever in particular generates high morbidity and mortality in West Africa, where the disease is endemic, and a recent outbreak in Nigeria was larger and more geog...
Autores principales: | Madu, Ikenna G., Files, Megan, Gharaibeh, Dima N., Moore, Amy L., Jung, Kie-Hoon, Gowen, Brian B., Dai, Dongcheng, Jones, Kevin F., Tyavanagimatt, Shanthakumar R., Burgeson, James R., Korth, Marcus J., Bedard, Kristin M., Iadonato, Shawn P., Amberg, Sean M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322784/ https://www.ncbi.nlm.nih.gov/pubmed/30576397 http://dx.doi.org/10.1371/journal.ppat.1007439 |
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