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Role of the pre-initiation complex in Mediator recruitment and dynamics

The Mediator complex stimulates the cooperative assembly of a pre-initiation complex (PIC) and recruitment of RNA Polymerase II (Pol II) for gene activation. The core Mediator complex is organized into head, middle, and tail modules, and in budding yeast (Saccharomyces cerevisiae), Mediator recruitm...

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Detalles Bibliográficos
Autores principales:	Knoll, Elisabeth R, Zhu, Z Iris, Sarkar, Debasish, Landsman, David, Morse, Randall H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322861/ https://www.ncbi.nlm.nih.gov/pubmed/30540252 http://dx.doi.org/10.7554/eLife.39633

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