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Development of immunocompatible pluripotent stem cells via CRISPR-based human leukocyte antigen engineering

Pluripotent stem cell transplantation is a promising regenerative strategy for treating intractable diseases. However, securing human leukocyte antigen (HLA)-matched donor stem cells is extremely difficult. The traditional approach for generating such cells is to establish homozygous pluripotent ste...

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Detalles Bibliográficos
Autores principales:	Jang, Yeonsue, Choi, Jinhyeok, Park, Narae, Kang, Jaewoo, Kim, Myungshin, Kim, Yonggoo, Ju, Ji Hyeon
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323054/ https://www.ncbi.nlm.nih.gov/pubmed/30617277 http://dx.doi.org/10.1038/s12276-018-0190-2

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