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Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis
OBJECTIVE: Extracellular matrix remodeling is required for adipose expansion under increased caloric intake. In turn, inhibited expandability due to aberrant collagen deposition promotes insulin resistance and progression towards the metabolic syndrome. An emerging role for the small leucine-rich pr...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323191/ https://www.ncbi.nlm.nih.gov/pubmed/30409703 http://dx.doi.org/10.1016/j.molmet.2018.10.007 |