Diet-dependent function of the extracellular matrix proteoglycan Lumican in obesity and glucose homeostasis

OBJECTIVE: Extracellular matrix remodeling is required for adipose expansion under increased caloric intake. In turn, inhibited expandability due to aberrant collagen deposition promotes insulin resistance and progression towards the metabolic syndrome. An emerging role for the small leucine-rich pr...

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Detalles Bibliográficos
Autores principales: Wolff, G., Taranko, A.E., Meln, I., Weinmann, J., Sijmonsma, T., Lerch, S., Heide, D., Billeter, A.T., Tews, D., Krunic, D., Fischer-Posovszky, P., Müller-Stich, B.P., Herzig, S., Grimm, D., Heikenwälder, M., Kao, W.W., Vegiopoulos, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323191/
https://www.ncbi.nlm.nih.gov/pubmed/30409703
http://dx.doi.org/10.1016/j.molmet.2018.10.007

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