Cargando…

Identification of putative drugs for gastric adenocarcinoma utilizing differentially expressed genes and connectivity map

Gastric adenocarcinoma (GAC) is a challenging disease with dim prognosis even after surgery; hence, novel treatments for GAC are in urgent need. The aim of the present study was to explore new potential compounds interfering with the key pathways related to GAC progression. The differentially expres...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Zu-Xuan, Zou, Xiao-Ping, Yan, Huang-Qun, Zhang, Rui, Pang, Jin-Shu, Qin, Xin-Gan, He, Rong-Quan, Ma, Jie, Feng, Zhen-Bo, Chen, Gang, Gan, Ting-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2019
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323227/ https://www.ncbi.nlm.nih.gov/pubmed/30569111 http://dx.doi.org/10.3892/mmr.2018.9758

Ejemplares similares

Comparative analysis of gene expression profiles of gastric cardia adenocarcinoma and gastric non-cardia adenocarcinoma
por: Song, Bin, et al.
Publicado: (2016)

Downregulation of HOXA3 in lung adenocarcinoma and its relevant molecular mechanism analysed by RT-qPCR, TCGA and in silico analysis
por: Gan, Bin-Liang, et al.
Publicado: (2018)

Significance of Glutathione Peroxidase 1 and Caudal-Related Homeodomain Transcription Factor in Human Gastric Adenocarcinoma
por: Han, Jing Jing, et al.
Publicado: (2013)

Mucinous adenocarcinoma and non-mucinous adenocarcinoma: differing clinicopathological characteristics and computed tomography features in gastric cancer
por: Zhao, Jianxi, et al.
Publicado: (2017)

LPCAT1 enhances the invasion and migration in gastric cancer: Based on computational biology methods and in vitro experiments
por: Chen, Zu‐Xuan, et al.
Publicado: (2023)

Expression of Das-1, Ki67 and sulfuric proteins in gastric cardia adenocarcinoma and intestinal metaplasia lesions
por: FENG, XIAO-SHAN, et al.
Publicado: (2013)

Putative effectors for prognosis in lung adenocarcinoma are ethnic and gender specific
por: Woolston, Andrew, et al.
Publicado: (2015)

Risk Factors and Their Diagnostic Values for Ocular Metastases in Gastric Adenocarcinoma
por: Chen, Yue, et al.
Publicado: (2021)

Clinical Value and Prospective Pathway Signaling of MicroRNA-375 in Lung Adenocarcinoma: A Study Based on the Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO) and Bioinformatics Analysis
por: Gan, Ting-qing, et al.
Publicado: (2017)

Oncogenic role of miR-183-5p in lung adenocarcinoma: A comprehensive study of qPCR, in vitro experiments and bioinformatic analysis
por: He, Rong-Quan, et al.
Publicado: (2018)

FGFR1 is an independent prognostic factor and can be regulated by miR-497 in gastric cancer progression
por: Xie, Gang, et al.
Publicado: (2018)

Risk Factors and Prognostic Significance of Retropancreatic Lymph Nodes in Gastric Adenocarcinoma
por: Xue, Lian, et al.
Publicado: (2015)

Circular RNA circSEC24A Promotes Cutaneous Squamous Cell Carcinoma Progression by Regulating miR-1193/MAP3K9 Axis
por: Lu, Xiaoyan, et al.
Publicado: (2021)

Clinical significance of putative markers of cancer stem cells in gastric cancer: A retrospective cohort study
por: Chen, Xiao-Long, et al.
Publicado: (2016)

Predicting Individual Pain Thresholds From Morphological Connectivity Using Structural MRI: A Multivariate Analysis Study
por: Zou, Rushi, et al.
Publicado: (2021)

Putative Connections Between Nitrate Reductase S-Nitrosylation and NO Synthesis Under Pathogen Attacks and Abiotic Stresses
por: Fu, Yu-Fan, et al.
Publicado: (2018)

Clinicopathological and molecular characteristics of synchronous gastric adenocarcinoma and gastrointestinal stromal tumors
por: Luo, Jun-Ming, et al.
Publicado: (2017)

Integrative analysis of metabolome and gut microbiota in Patients with pancreatic ductal adenocarcinoma
por: Guo, Xiaodong, et al.
Publicado: (2022)

A meta-analysis of the lymphatic microvessel density and survival in gastric cancer with 1809 cases
por: Liang, Liang, et al.
Publicado: (2017)

Bisdemethoxycurcumin attenuates gastric adenocarcinoma growth by inducing mitochondrial dysfunction
por: LUO, CHANGJIANG, et al.
Publicado: (2015)

Bioinformatic evidences and analysis of putative biomarkers in pancreatic ductal adenocarcinoma
por: Gu, Yuan, et al.
Publicado: (2019)

EFCC1 as a putative prognostic biomarker in lung adenocarcinoma
por: Yu, Shengnan, et al.
Publicado: (2020)

Clinical utility of diagnostic guidelines and putative biomarkers in lymphangioleiomyomatosis
por: Chang, William YC, et al.
Publicado: (2012)

Downregulation of hsa-microRNA-204-5p and identification of its potential regulatory network in non-small cell lung cancer: RT-qPCR, bioinformatic- and meta-analyses
por: Liang, Chang-Yu, et al.
Publicado: (2020)

Downregulation of connective tissue growth factor inhibits the growth and invasion of gastric cancer cells and attenuates peritoneal dissemination
por: Jiang, Cheng-Gang, et al.
Publicado: (2011)

A Case of Complete Remission from Advanced Gastric Adenocarcinoma with Synchronous Liver Metastasis in Response to EOX Chemotherapy
por: Yan, Zhi-jun, et al.
Publicado: (2018)

Metastasis, Risk Factors and Prognostic Significance of Splenic Hilar Lymph Nodes in Gastric Adenocarcinoma
por: Chen, Xiao-Long, et al.
Publicado: (2014)

Identification of putative fecundity-related gustatory receptor genes in the brown planthopper Nilaparvata lugens
por: Kang, Kui, et al.
Publicado: (2018)

The putative pleiotropic functions of meprin β in gastric cancer
por: Siemsen, Wiebke, et al.
Publicado: (2023)

The putative role of ferroptosis in gastric cancer: a review
por: Wang, Li, et al.
Publicado: (2023)

The Gastric Microbiome Is Perturbed in Advanced Gastric Adenocarcinoma Identified Through Shotgun Metagenomics
por: Hu, Yuan-Liang, et al.
Publicado: (2018)

CyclinD1 and p57(kip2) as biomarkers in differentiation, metastasis and prognosis of gastric cardia adenocarcinoma
por: Ru, Yi, et al.
Publicado: (2017)

Prognostic Values for the mRNA Expression of the ADAMTS Family of Genes in Gastric Cancer
por: Liang, Liang, et al.
Publicado: (2020)

Combining Regional and Connectivity Metrics of Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging for Individualized Prediction of Pain Sensitivity
por: Zou, Rushi, et al.
Publicado: (2022)

Molecular Mapping of Putative Genomic Regions Controlling Fruit and Seed Morphology of Watermelon
por: Yang, Tiantian, et al.
Publicado: (2023)

Preoperative albumin-to-fibrinogen ratio predicts severe postoperative complications in elderly gastric cancer subjects after radical laparoscopic gastrectomy
por: You, Xuexue, et al.
Publicado: (2019)

Discovery of putative capsaicin biosynthetic genes by RNA-Seq and digital gene expression analysis of pepper
por: Zhang, Zi-Xin, et al.
Publicado: (2016)

A survival comparison of gastric mucin-producing adenocarcinoma to conventional adenocarcinoma: a SEER database analysis
por: Wang, Qiang, et al.
Publicado: (2021)

CT volumetry for gastric adenocarcinoma: association with lymphovascular invasion and T-stages
por: Chen, Xiao-Li, et al.
Publicado: (2017)

HnRNPR-CCNB1/CENPF axis contributes to gastric cancer proliferation and metastasis
por: Chen, Er-Bao, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5d73628mlva995b6nt336dkguo