MEK inhibitor enhanced the antitumor effect of oxaliplatin and 5-fluorouracil in MEK1 Q56P-mutant colorectal cancer cells

Mitogen-activated protein kinase kinase (MEK) small molecule inhibitors have been investigated in preclinical or clinical trials for the treatment of cancer. In the present study the genetic test results of 120 patients with colorectal cancer (CRC) were screened and the mutation rate of MEK1 was ide...

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Detalles Bibliográficos
Autores principales: Jing, Changwen, Li, Huizi, Du, Yuanyuan, Cao, Haixia, Liu, Siwen, Wang, Zhuo, Ma, Rong, Feng, Jifeng, Wu, Jianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323316/
https://www.ncbi.nlm.nih.gov/pubmed/30535504
http://dx.doi.org/10.3892/mmr.2018.9730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323316/
https://www.ncbi.nlm.nih.gov/pubmed/30535504
http://dx.doi.org/10.3892/mmr.2018.9730

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