A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease

Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without...

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Autores principales: Aravamudan, Veeraraghavan Meyyur, Er, Chaozer, Hussain, Ikram, Cheong, Nicholas wong wai, Chern Hao, Chong, Kuthah, Navin, En-Xian Tan, Emily, Fan, Bingwen Eugene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323427/
https://www.ncbi.nlm.nih.gov/pubmed/30675165
http://dx.doi.org/10.1155/2018/8057045
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author Aravamudan, Veeraraghavan Meyyur
Er, Chaozer
Hussain, Ikram
Cheong, Nicholas wong wai
Chern Hao, Chong
Kuthah, Navin
En-Xian Tan, Emily
Fan, Bingwen Eugene
author_facet Aravamudan, Veeraraghavan Meyyur
Er, Chaozer
Hussain, Ikram
Cheong, Nicholas wong wai
Chern Hao, Chong
Kuthah, Navin
En-Xian Tan, Emily
Fan, Bingwen Eugene
author_sort Aravamudan, Veeraraghavan Meyyur
collection PubMed
description Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature.
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spelling pubmed-63234272019-01-23 A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease Aravamudan, Veeraraghavan Meyyur Er, Chaozer Hussain, Ikram Cheong, Nicholas wong wai Chern Hao, Chong Kuthah, Navin En-Xian Tan, Emily Fan, Bingwen Eugene Case Rep Med Case Report Hemophagocytic lymphohistiocytosis (HLH) is rare and life-threatening medical emergency. Parvovirus infection is rarely associated with HLH. We report a case of parvovirus-related HLH in a patient with alpha thalassaemia (HbH disease). The patient responded well to a course of dexamethasone without the need of etoposide. Based on our literature search, this is the first case of parvovirus related HLH in a patient with HbH disease in the medical literature. Hindawi 2018-12-24 /pmc/articles/PMC6323427/ /pubmed/30675165 http://dx.doi.org/10.1155/2018/8057045 Text en Copyright © 2018 Veeraraghavan Meyyur Aravamudan et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Aravamudan, Veeraraghavan Meyyur
Er, Chaozer
Hussain, Ikram
Cheong, Nicholas wong wai
Chern Hao, Chong
Kuthah, Navin
En-Xian Tan, Emily
Fan, Bingwen Eugene
A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease
title A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease
title_full A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease
title_fullStr A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease
title_full_unstemmed A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease
title_short A Case of Parvovirus-Related Haemophagocytic Lymphohistiocytosis in a Patient with HbH Disease
title_sort case of parvovirus-related haemophagocytic lymphohistiocytosis in a patient with hbh disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323427/
https://www.ncbi.nlm.nih.gov/pubmed/30675165
http://dx.doi.org/10.1155/2018/8057045
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