M1-Polarized Macrophages Promote Self-Renewing Phenotype of Hepatic Progenitor Cells with Jagged1-Notch Signalling Involved: Relevance in Primary Sclerosing Cholangitis

The immunologic interaction between parenchyma cells and encircling inflammatory cells is thought to be the most important mechanism of biliary damage and repair in primary sclerosing cholangitis (PSC). Monocytes/macrophages as master regulators of hepatic inflammation have been demonstrated to cont...

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Detalles Bibliográficos
Autores principales: Li, Heli, Sun, Shiran, Lei, Qing, Lei, Ping, Cai, Xiong, Wan, Chidan, Shen, Guanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323443/
https://www.ncbi.nlm.nih.gov/pubmed/30671485
http://dx.doi.org/10.1155/2018/4807145

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