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PANCREATICODUODENECTOMY: IMPACT OF THE TECHNIQUE ON OPERATIVE OUTCOMES AND SURGICAL MORTALITY

BACKGROUND: Pancreaticoduodenectomy (PD) is a procedure associated with significant morbidity and mortality. Initially described as gastropancreaticoduodenectomy (GPD), the possibility of preservation of the gastric antrum and pylorus was described in the 1970s. AIM: To evaluate the mortality and op...

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Autores principales: REZENDE, Achiles Queiroz de Monteiro, DUTRA, João Paulo Simões, GESTIC, Martinho Antonio, UTRINI, Murillo Pimentel, CALLEJAS-NETO, Francisco, CHAIM, Elinton Adami, CAZZO, Everton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323629/
https://www.ncbi.nlm.nih.gov/pubmed/30624521
http://dx.doi.org/10.1590/0102-672020180001e1412
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author REZENDE, Achiles Queiroz de Monteiro
DUTRA, João Paulo Simões
GESTIC, Martinho Antonio
UTRINI, Murillo Pimentel
CALLEJAS-NETO, Francisco
CHAIM, Elinton Adami
CAZZO, Everton
author_facet REZENDE, Achiles Queiroz de Monteiro
DUTRA, João Paulo Simões
GESTIC, Martinho Antonio
UTRINI, Murillo Pimentel
CALLEJAS-NETO, Francisco
CHAIM, Elinton Adami
CAZZO, Everton
author_sort REZENDE, Achiles Queiroz de Monteiro
collection PubMed
description BACKGROUND: Pancreaticoduodenectomy (PD) is a procedure associated with significant morbidity and mortality. Initially described as gastropancreaticoduodenectomy (GPD), the possibility of preservation of the gastric antrum and pylorus was described in the 1970s. AIM: To evaluate the mortality and operative variables of PD with or without pyloric preservation and to correlate them with the adopted technique and surgical indication. METHOD: Retrospective cohort on data analysis of medical records of individuals who underwent PD from 2012 through 2017. Demographic, anthropometric and operative variables were analyzed and correlated with the adopted technique (GPD vs. PD) and the surgical indication. RESULTS: Of the 87 individuals evaluated, 38 (43.7%) underwent GPD and 49 (53.3%) were submitted to PD. The frequency of GPD (62.5%) was significantly higher among patients with pancreatic neoplasia (p=0.04). The hospital stay was significantly shorter among the individuals submitted to resection due to neoplasias of less aggressive behavior (p=0.04). Surgical mortality was 10.3%, with no difference between GPD and PD. Mortality was significantly higher among individuals undergoing resection for chronic pancreatitis (p=0.001). CONCLUSION: There were no differences in mortality, surgical time, bleeding or hospitalization time between GPD and PD. Pancreas head neoplasm was associated with a higher indication of GPD. Resection of less aggressive neoplasms was associated with lower morbidity and mortality.
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spelling pubmed-63236292019-01-14 PANCREATICODUODENECTOMY: IMPACT OF THE TECHNIQUE ON OPERATIVE OUTCOMES AND SURGICAL MORTALITY REZENDE, Achiles Queiroz de Monteiro DUTRA, João Paulo Simões GESTIC, Martinho Antonio UTRINI, Murillo Pimentel CALLEJAS-NETO, Francisco CHAIM, Elinton Adami CAZZO, Everton Arq Bras Cir Dig Original Article BACKGROUND: Pancreaticoduodenectomy (PD) is a procedure associated with significant morbidity and mortality. Initially described as gastropancreaticoduodenectomy (GPD), the possibility of preservation of the gastric antrum and pylorus was described in the 1970s. AIM: To evaluate the mortality and operative variables of PD with or without pyloric preservation and to correlate them with the adopted technique and surgical indication. METHOD: Retrospective cohort on data analysis of medical records of individuals who underwent PD from 2012 through 2017. Demographic, anthropometric and operative variables were analyzed and correlated with the adopted technique (GPD vs. PD) and the surgical indication. RESULTS: Of the 87 individuals evaluated, 38 (43.7%) underwent GPD and 49 (53.3%) were submitted to PD. The frequency of GPD (62.5%) was significantly higher among patients with pancreatic neoplasia (p=0.04). The hospital stay was significantly shorter among the individuals submitted to resection due to neoplasias of less aggressive behavior (p=0.04). Surgical mortality was 10.3%, with no difference between GPD and PD. Mortality was significantly higher among individuals undergoing resection for chronic pancreatitis (p=0.001). CONCLUSION: There were no differences in mortality, surgical time, bleeding or hospitalization time between GPD and PD. Pancreas head neoplasm was associated with a higher indication of GPD. Resection of less aggressive neoplasms was associated with lower morbidity and mortality. Colégio Brasileiro de Cirurgia Digestiva 2019-01-07 /pmc/articles/PMC6323629/ /pubmed/30624521 http://dx.doi.org/10.1590/0102-672020180001e1412 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
REZENDE, Achiles Queiroz de Monteiro
DUTRA, João Paulo Simões
GESTIC, Martinho Antonio
UTRINI, Murillo Pimentel
CALLEJAS-NETO, Francisco
CHAIM, Elinton Adami
CAZZO, Everton
PANCREATICODUODENECTOMY: IMPACT OF THE TECHNIQUE ON OPERATIVE OUTCOMES AND SURGICAL MORTALITY
title PANCREATICODUODENECTOMY: IMPACT OF THE TECHNIQUE ON OPERATIVE OUTCOMES AND SURGICAL MORTALITY
title_full PANCREATICODUODENECTOMY: IMPACT OF THE TECHNIQUE ON OPERATIVE OUTCOMES AND SURGICAL MORTALITY
title_fullStr PANCREATICODUODENECTOMY: IMPACT OF THE TECHNIQUE ON OPERATIVE OUTCOMES AND SURGICAL MORTALITY
title_full_unstemmed PANCREATICODUODENECTOMY: IMPACT OF THE TECHNIQUE ON OPERATIVE OUTCOMES AND SURGICAL MORTALITY
title_short PANCREATICODUODENECTOMY: IMPACT OF THE TECHNIQUE ON OPERATIVE OUTCOMES AND SURGICAL MORTALITY
title_sort pancreaticoduodenectomy: impact of the technique on operative outcomes and surgical mortality
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323629/
https://www.ncbi.nlm.nih.gov/pubmed/30624521
http://dx.doi.org/10.1590/0102-672020180001e1412
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