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Increased neutrophil extracellular traps activate NLRP3 and inflammatory macrophages in adult-onset Still’s disease
BACKGROUND: Adult-onset Still’s disease (AOSD) is a systemic inflammatory disease characterized by neutrophilia and NLRP3 inflammasome and macrophage activation. We investigated the role of neutrophil extracellular traps (NETs) in the pathogenesis of AOSD, and explored the effect of NETs on activati...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323819/ https://www.ncbi.nlm.nih.gov/pubmed/30616678 http://dx.doi.org/10.1186/s13075-018-1800-z |