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Increased neutrophil extracellular traps activate NLRP3 and inflammatory macrophages in adult-onset Still’s disease

BACKGROUND: Adult-onset Still’s disease (AOSD) is a systemic inflammatory disease characterized by neutrophilia and NLRP3 inflammasome and macrophage activation. We investigated the role of neutrophil extracellular traps (NETs) in the pathogenesis of AOSD, and explored the effect of NETs on activati...

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Detalles Bibliográficos
Autores principales:	Hu, Qiongyi, Shi, Hui, Zeng, Ting, Liu, Honglei, Su, Yutong, Cheng, Xiaobing, Ye, Junna, Yin, Yufeng, Liu, Mengru, Zheng, Hui, Wu, Xinyao, Chi, Huihui, Zhou, Zhuochao, Jia, Jinchao, Sun, Yue, Teng, Jialin, Yang, Chengde
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323819/ https://www.ncbi.nlm.nih.gov/pubmed/30616678 http://dx.doi.org/10.1186/s13075-018-1800-z

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