canSAR: update to the cancer translational research and drug discovery knowledgebase

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canSAR (http://cansar.icr.ac.uk) is a public, freely available, integrative translational research and drug discovery knowlegebase. canSAR informs researchers to help solve key bottlenecks in cancer translation and drug discovery. It integrates genomic, protein, pharmacological, drug and chemical da...

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Detalles Bibliográficos
Autores principales: Coker, Elizabeth A, Mitsopoulos, Costas, Tym, Joesph E, Komianou, Angeliki, Kannas, Christos, Di Micco, Patrizio, Villasclaras Fernandez, Eloy, Ozer, Bugra, Antolin, Albert A, Workman, Paul, Al-Lazikani, Bissan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323893/
https://www.ncbi.nlm.nih.gov/pubmed/30496479
http://dx.doi.org/10.1093/nar/gky1129
Descripción
Sumario:canSAR (http://cansar.icr.ac.uk) is a public, freely available, integrative translational research and drug discovery knowlegebase. canSAR informs researchers to help solve key bottlenecks in cancer translation and drug discovery. It integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and unique, comprehensive and orthogonal ‘druggability’ assessments. canSAR is widely used internationally by academia and industry. Here we describe major enhancements to canSAR including new and expanded data. We also describe the first components of canSARblack—an advanced, responsive, multi-device compatible redesign of canSAR with a question-led interface.

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