canSAR: update to the cancer translational research and drug discovery knowledgebase

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canSAR (http://cansar.icr.ac.uk) is a public, freely available, integrative translational research and drug discovery knowlegebase. canSAR informs researchers to help solve key bottlenecks in cancer translation and drug discovery. It integrates genomic, protein, pharmacological, drug and chemical da...

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Autores principales: Coker, Elizabeth A, Mitsopoulos, Costas, Tym, Joesph E, Komianou, Angeliki, Kannas, Christos, Di Micco, Patrizio, Villasclaras Fernandez, Eloy, Ozer, Bugra, Antolin, Albert A, Workman, Paul, Al-Lazikani, Bissan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323893/
https://www.ncbi.nlm.nih.gov/pubmed/30496479
http://dx.doi.org/10.1093/nar/gky1129
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author Coker, Elizabeth A
Mitsopoulos, Costas
Tym, Joesph E
Komianou, Angeliki
Kannas, Christos
Di Micco, Patrizio
Villasclaras Fernandez, Eloy
Ozer, Bugra
Antolin, Albert A
Workman, Paul
Al-Lazikani, Bissan
author_facet Coker, Elizabeth A
Mitsopoulos, Costas
Tym, Joesph E
Komianou, Angeliki
Kannas, Christos
Di Micco, Patrizio
Villasclaras Fernandez, Eloy
Ozer, Bugra
Antolin, Albert A
Workman, Paul
Al-Lazikani, Bissan
author_sort Coker, Elizabeth A
collection PubMed
description canSAR (http://cansar.icr.ac.uk) is a public, freely available, integrative translational research and drug discovery knowlegebase. canSAR informs researchers to help solve key bottlenecks in cancer translation and drug discovery. It integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and unique, comprehensive and orthogonal ‘druggability’ assessments. canSAR is widely used internationally by academia and industry. Here we describe major enhancements to canSAR including new and expanded data. We also describe the first components of canSARblack—an advanced, responsive, multi-device compatible redesign of canSAR with a question-led interface.
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spelling pubmed-63238932019-01-10 canSAR: update to the cancer translational research and drug discovery knowledgebase Coker, Elizabeth A Mitsopoulos, Costas Tym, Joesph E Komianou, Angeliki Kannas, Christos Di Micco, Patrizio Villasclaras Fernandez, Eloy Ozer, Bugra Antolin, Albert A Workman, Paul Al-Lazikani, Bissan Nucleic Acids Res Database Issue canSAR (http://cansar.icr.ac.uk) is a public, freely available, integrative translational research and drug discovery knowlegebase. canSAR informs researchers to help solve key bottlenecks in cancer translation and drug discovery. It integrates genomic, protein, pharmacological, drug and chemical data with structural biology, protein networks and unique, comprehensive and orthogonal ‘druggability’ assessments. canSAR is widely used internationally by academia and industry. Here we describe major enhancements to canSAR including new and expanded data. We also describe the first components of canSARblack—an advanced, responsive, multi-device compatible redesign of canSAR with a question-led interface. Oxford University Press 2019-01-08 2018-11-28 /pmc/articles/PMC6323893/ /pubmed/30496479 http://dx.doi.org/10.1093/nar/gky1129 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Issue
Coker, Elizabeth A
Mitsopoulos, Costas
Tym, Joesph E
Komianou, Angeliki
Kannas, Christos
Di Micco, Patrizio
Villasclaras Fernandez, Eloy
Ozer, Bugra
Antolin, Albert A
Workman, Paul
Al-Lazikani, Bissan
canSAR: update to the cancer translational research and drug discovery knowledgebase
title canSAR: update to the cancer translational research and drug discovery knowledgebase
title_full canSAR: update to the cancer translational research and drug discovery knowledgebase
title_fullStr canSAR: update to the cancer translational research and drug discovery knowledgebase
title_full_unstemmed canSAR: update to the cancer translational research and drug discovery knowledgebase
title_short canSAR: update to the cancer translational research and drug discovery knowledgebase
title_sort cansar: update to the cancer translational research and drug discovery knowledgebase
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323893/
https://www.ncbi.nlm.nih.gov/pubmed/30496479
http://dx.doi.org/10.1093/nar/gky1129
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