The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters

Natural products originating from microorganisms are frequently used in antimicrobial and anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing availability of microbial genome data has made it possible to access the wealth of biosynthetic clusters responsible for...

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Autores principales: Blin, Kai, Pascal Andreu, Victòria, de los Santos, Emmanuel L C, Del Carratore, Francesco, Lee, Sang Yup, Medema, Marnix H, Weber, Tilmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324005/
https://www.ncbi.nlm.nih.gov/pubmed/30395294
http://dx.doi.org/10.1093/nar/gky1060
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author Blin, Kai
Pascal Andreu, Victòria
de los Santos, Emmanuel L C
Del Carratore, Francesco
Lee, Sang Yup
Medema, Marnix H
Weber, Tilmann
author_facet Blin, Kai
Pascal Andreu, Victòria
de los Santos, Emmanuel L C
Del Carratore, Francesco
Lee, Sang Yup
Medema, Marnix H
Weber, Tilmann
author_sort Blin, Kai
collection PubMed
description Natural products originating from microorganisms are frequently used in antimicrobial and anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing availability of microbial genome data has made it possible to access the wealth of biosynthetic clusters responsible for the production of these compounds by genome mining. antiSMASH is one of the most popular tools in this field. The antiSMASH database provides pre-computed antiSMASH results for many publicly available microbial genomes and allows for advanced cross-genome searches. The current version 2 of the antiSMASH database contains annotations for 6200 full bacterial genomes and 18,576 bacterial draft genomes and is available at https://antismash-db.secondarymetabolites.org/.
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spelling pubmed-63240052019-01-10 The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters Blin, Kai Pascal Andreu, Victòria de los Santos, Emmanuel L C Del Carratore, Francesco Lee, Sang Yup Medema, Marnix H Weber, Tilmann Nucleic Acids Res Database Issue Natural products originating from microorganisms are frequently used in antimicrobial and anticancer drugs, pesticides, herbicides or fungicides. In the last years, the increasing availability of microbial genome data has made it possible to access the wealth of biosynthetic clusters responsible for the production of these compounds by genome mining. antiSMASH is one of the most popular tools in this field. The antiSMASH database provides pre-computed antiSMASH results for many publicly available microbial genomes and allows for advanced cross-genome searches. The current version 2 of the antiSMASH database contains annotations for 6200 full bacterial genomes and 18,576 bacterial draft genomes and is available at https://antismash-db.secondarymetabolites.org/. Oxford University Press 2019-01-08 2018-11-05 /pmc/articles/PMC6324005/ /pubmed/30395294 http://dx.doi.org/10.1093/nar/gky1060 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Nucleic Acids Research. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Issue
Blin, Kai
Pascal Andreu, Victòria
de los Santos, Emmanuel L C
Del Carratore, Francesco
Lee, Sang Yup
Medema, Marnix H
Weber, Tilmann
The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
title The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
title_full The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
title_fullStr The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
title_full_unstemmed The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
title_short The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
title_sort antismash database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324005/
https://www.ncbi.nlm.nih.gov/pubmed/30395294
http://dx.doi.org/10.1093/nar/gky1060
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