Cargando…
Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer
Aberrant activation of epithelial-mesenchymal transition (EMT) in carcinoma cells contributes to increased migration and invasion, metastasis, drug resistance, and tumor-initiating capacity. EMT is not always a binary process; rather, cells may exhibit a hybrid epithelial/mesenchymal (E/M) phenotype...
Autores principales: | Jolly, Mohit Kumar, Preca, Bogdan-Tiberius, Tripathi, Satyendra C., Jia, Dongya, George, Jason T., Hanash, Samir M., Brabletz, Thomas, Stemmler, Marc P., Maurer, Jochen, Levine, Herbert |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AIP Publishing LLC
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324214/ https://www.ncbi.nlm.nih.gov/pubmed/31069317 http://dx.doi.org/10.1063/1.5024874 |
Ejemplares similares
-
A novel ZEB1/HAS2 positive feedback loop promotes EMT in breast cancer
por: Preca, Bogdan-Tiberius, et al.
Publicado: (2017) -
The EMT-activator ZEB1 induces bone metastasis associated genes including BMP-inhibitors
por: Mock, Kerstin, et al.
Publicado: (2015) -
Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?
por: Jolly, Mohit Kumar, et al.
Publicado: (2017) -
Numb prevents a complete epithelial–mesenchymal transition by modulating Notch signalling
por: Bocci, Federico, et al.
Publicado: (2017) -
Stability of the hybrid epithelial/mesenchymal phenotype
por: Jolly, Mohit Kumar, et al.
Publicado: (2016)