Murine Methyl Donor Deficiency Impairs Early Growth in Association with Dysmorphic Small Intestinal Crypts and Reduced Gut Microbial Community Diversity

BACKGROUND: Folate and choline are essential methyl donor nutrients throughout the life span; however, the adverse effects of combined deficiency on early growth, intestinal epithelial morphology, and the gut microbiome remain only partially understood. OBJECTIVES: We investigated the effects of die...

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Detalles Bibliográficos
Autores principales: Alves da Silva, Antonio V, de Castro Oliveira, Stephanie B, Di Rienzi, Sara C, Brown-Steinke, Kathleen, Dehan, Lauren M, Rood, Jill K, Carreira, Vinicius S, Le, Hung, Maier, Elizabeth A, Betz, Kristina J, Aihara, Eitaro, Ley, Ruth E, Preidis, Geoffrey A, Shen, Lanlan, Moore, Sean R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324351/
http://dx.doi.org/10.1093/cdn/nzy070

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