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The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae
In the Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae (CRACKLE), trimethoprim-sulfamethoxazole (TMP-SMX) had a limited role in the treatment of less severe carbapenem-resistant Enterobacteriaceae (CRE) infections, especially urinary tract infections. Of teste...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324543/ https://www.ncbi.nlm.nih.gov/pubmed/30631796 http://dx.doi.org/10.1093/ofid/ofy351 |
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author | Luterbach, Courtney L Boshe, Ashley Henderson, Heather I Cober, Eric Richter, Sandra S Salata, Robert A Kalayjian, Robert C Watkins, Richard R Hujer, Andrea M Hujer, Kristine M Rudin, Susan D Domitrovic, T Nicholas Doi, Yohei Kaye, Keith S Evans, Scott Fowler, Vance G Bonomo, Robert A van Duin, David |
author_facet | Luterbach, Courtney L Boshe, Ashley Henderson, Heather I Cober, Eric Richter, Sandra S Salata, Robert A Kalayjian, Robert C Watkins, Richard R Hujer, Andrea M Hujer, Kristine M Rudin, Susan D Domitrovic, T Nicholas Doi, Yohei Kaye, Keith S Evans, Scott Fowler, Vance G Bonomo, Robert A van Duin, David |
author_sort | Luterbach, Courtney L |
collection | PubMed |
description | In the Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae (CRACKLE), trimethoprim-sulfamethoxazole (TMP-SMX) had a limited role in the treatment of less severe carbapenem-resistant Enterobacteriaceae (CRE) infections, especially urinary tract infections. Of tested CRE, only 29% were susceptible to TMP-SMX. Development of resistance further limits the use of TMP-SMX in CRE infections. |
format | Online Article Text |
id | pubmed-6324543 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-63245432019-01-10 The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae Luterbach, Courtney L Boshe, Ashley Henderson, Heather I Cober, Eric Richter, Sandra S Salata, Robert A Kalayjian, Robert C Watkins, Richard R Hujer, Andrea M Hujer, Kristine M Rudin, Susan D Domitrovic, T Nicholas Doi, Yohei Kaye, Keith S Evans, Scott Fowler, Vance G Bonomo, Robert A van Duin, David Open Forum Infect Dis Brief Report In the Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae (CRACKLE), trimethoprim-sulfamethoxazole (TMP-SMX) had a limited role in the treatment of less severe carbapenem-resistant Enterobacteriaceae (CRE) infections, especially urinary tract infections. Of tested CRE, only 29% were susceptible to TMP-SMX. Development of resistance further limits the use of TMP-SMX in CRE infections. Oxford University Press 2018-12-14 /pmc/articles/PMC6324543/ /pubmed/30631796 http://dx.doi.org/10.1093/ofid/ofy351 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Brief Report Luterbach, Courtney L Boshe, Ashley Henderson, Heather I Cober, Eric Richter, Sandra S Salata, Robert A Kalayjian, Robert C Watkins, Richard R Hujer, Andrea M Hujer, Kristine M Rudin, Susan D Domitrovic, T Nicholas Doi, Yohei Kaye, Keith S Evans, Scott Fowler, Vance G Bonomo, Robert A van Duin, David The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae |
title | The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae |
title_full | The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae |
title_fullStr | The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae |
title_full_unstemmed | The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae |
title_short | The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae |
title_sort | role of trimethoprim/sulfamethoxazole in the treatment of infections caused by carbapenem-resistant enterobacteriaceae |
topic | Brief Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324543/ https://www.ncbi.nlm.nih.gov/pubmed/30631796 http://dx.doi.org/10.1093/ofid/ofy351 |
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