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The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae

In the Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae (CRACKLE), trimethoprim-sulfamethoxazole (TMP-SMX) had a limited role in the treatment of less severe carbapenem-resistant Enterobacteriaceae (CRE) infections, especially urinary tract infections. Of teste...

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Autores principales: Luterbach, Courtney L, Boshe, Ashley, Henderson, Heather I, Cober, Eric, Richter, Sandra S, Salata, Robert A, Kalayjian, Robert C, Watkins, Richard R, Hujer, Andrea M, Hujer, Kristine M, Rudin, Susan D, Domitrovic, T Nicholas, Doi, Yohei, Kaye, Keith S, Evans, Scott, Fowler, Vance G, Bonomo, Robert A, van Duin, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324543/
https://www.ncbi.nlm.nih.gov/pubmed/30631796
http://dx.doi.org/10.1093/ofid/ofy351
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author Luterbach, Courtney L
Boshe, Ashley
Henderson, Heather I
Cober, Eric
Richter, Sandra S
Salata, Robert A
Kalayjian, Robert C
Watkins, Richard R
Hujer, Andrea M
Hujer, Kristine M
Rudin, Susan D
Domitrovic, T Nicholas
Doi, Yohei
Kaye, Keith S
Evans, Scott
Fowler, Vance G
Bonomo, Robert A
van Duin, David
author_facet Luterbach, Courtney L
Boshe, Ashley
Henderson, Heather I
Cober, Eric
Richter, Sandra S
Salata, Robert A
Kalayjian, Robert C
Watkins, Richard R
Hujer, Andrea M
Hujer, Kristine M
Rudin, Susan D
Domitrovic, T Nicholas
Doi, Yohei
Kaye, Keith S
Evans, Scott
Fowler, Vance G
Bonomo, Robert A
van Duin, David
author_sort Luterbach, Courtney L
collection PubMed
description In the Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae (CRACKLE), trimethoprim-sulfamethoxazole (TMP-SMX) had a limited role in the treatment of less severe carbapenem-resistant Enterobacteriaceae (CRE) infections, especially urinary tract infections. Of tested CRE, only 29% were susceptible to TMP-SMX. Development of resistance further limits the use of TMP-SMX in CRE infections.
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spelling pubmed-63245432019-01-10 The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae Luterbach, Courtney L Boshe, Ashley Henderson, Heather I Cober, Eric Richter, Sandra S Salata, Robert A Kalayjian, Robert C Watkins, Richard R Hujer, Andrea M Hujer, Kristine M Rudin, Susan D Domitrovic, T Nicholas Doi, Yohei Kaye, Keith S Evans, Scott Fowler, Vance G Bonomo, Robert A van Duin, David Open Forum Infect Dis Brief Report In the Consortium on Resistance Against Carbapenems in Klebsiella and other Enterobacteriaceae (CRACKLE), trimethoprim-sulfamethoxazole (TMP-SMX) had a limited role in the treatment of less severe carbapenem-resistant Enterobacteriaceae (CRE) infections, especially urinary tract infections. Of tested CRE, only 29% were susceptible to TMP-SMX. Development of resistance further limits the use of TMP-SMX in CRE infections. Oxford University Press 2018-12-14 /pmc/articles/PMC6324543/ /pubmed/30631796 http://dx.doi.org/10.1093/ofid/ofy351 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Luterbach, Courtney L
Boshe, Ashley
Henderson, Heather I
Cober, Eric
Richter, Sandra S
Salata, Robert A
Kalayjian, Robert C
Watkins, Richard R
Hujer, Andrea M
Hujer, Kristine M
Rudin, Susan D
Domitrovic, T Nicholas
Doi, Yohei
Kaye, Keith S
Evans, Scott
Fowler, Vance G
Bonomo, Robert A
van Duin, David
The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae
title The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae
title_full The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae
title_fullStr The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae
title_full_unstemmed The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae
title_short The Role of Trimethoprim/Sulfamethoxazole in the Treatment of Infections Caused by Carbapenem-Resistant Enterobacteriaceae
title_sort role of trimethoprim/sulfamethoxazole in the treatment of infections caused by carbapenem-resistant enterobacteriaceae
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324543/
https://www.ncbi.nlm.nih.gov/pubmed/30631796
http://dx.doi.org/10.1093/ofid/ofy351
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