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Long noncoding RNA SNHG16 induces sorafenib resistance in hepatocellular carcinoma cells through sponging miR-140-5p

BACKGROUND: Sorafenib is widely used for treatment of hepatocellular carcinoma (HCC), but the acquired resistance remains a major obstacle for its application. Thus it is of critical importance to elucidate the molecular mechanisms underlying sorafenib resistance in HCC. This study aimed to determin...

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Detalles Bibliográficos
Autores principales: Ye, Junfeng, Zhang, Ruoyan, Du, Xiaohong, Chai, Wengang, Zhou, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324603/
https://www.ncbi.nlm.nih.gov/pubmed/30655679
http://dx.doi.org/10.2147/OTT.S175176