Deletion of genes involved in the ketogluconate metabolism, Entner-Doudoroff pathway, and glucose dehydrogenase increase local and invasive virulence phenotypes in Streptococcus pneumoniae

Streptococcus pneumoniae displays increased resistance to antibiotic therapy following biofilm formation. A genome-wide search revealed that SP 0320 and SP 0675 (respectively annotated as 5-keto-D-gluconate-5-reductase and glucose dehydrogenase) contain the highest degree of homology to CsgA of Myxo...

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Detalles Bibliográficos
Autores principales: Hu, Fen Z., Król, Jarosław E., Tsai, Chen Hsuan Sherry, Eutsey, Rory A., Hiller, Luisa N., Sen, Bhaswati, Ahmed, Azad, Hillman, Todd, Buchinsky, Farrel J., Nistico, Laura, Dice, Bethany, Longwell, Mark, Horsey, Edward, Ehrlich, Garth D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324787/
https://www.ncbi.nlm.nih.gov/pubmed/30620734
http://dx.doi.org/10.1371/journal.pone.0209688

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324787/
https://www.ncbi.nlm.nih.gov/pubmed/30620734
http://dx.doi.org/10.1371/journal.pone.0209688

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