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Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature

Tuberculosis is the most frequent granulomatous disease but the involvement of the larynx is rare. Immunosuppressed patients have a higher risk of developing this clinical form due to primoinfection or reactivation of latent tuberculosis. It is common to confuse the diagnosis of laryngeal tuberculos...

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Autores principales: Hurtado Alegre, Jorge Luis, Trigoso Gutierrez, Anita, Matos Prado, Eduardo, Huaringa Marcelo, Jorge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324851/
https://www.ncbi.nlm.nih.gov/pubmed/30648077
http://dx.doi.org/10.7759/cureus.3545
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author Hurtado Alegre, Jorge Luis
Trigoso Gutierrez, Anita
Matos Prado, Eduardo
Huaringa Marcelo, Jorge
author_facet Hurtado Alegre, Jorge Luis
Trigoso Gutierrez, Anita
Matos Prado, Eduardo
Huaringa Marcelo, Jorge
author_sort Hurtado Alegre, Jorge Luis
collection PubMed
description Tuberculosis is the most frequent granulomatous disease but the involvement of the larynx is rare. Immunosuppressed patients have a higher risk of developing this clinical form due to primoinfection or reactivation of latent tuberculosis. It is common to confuse the diagnosis of laryngeal tuberculosis with laryngeal cancer because they have similar macroscopic lesions and both produce dysphonia of chronic evolution. We present the case of a pregnant woman with chronic dysphonia, dysphagia, and odynophagia, diagnosed initially with laryngeal cancer after the first laryngoscopy. However, the patient also presented with fever, productive cough, weight loss, and dyspnea. The sputum sample showed a positive result for acid-fast bacilli (AFB) test; chest X-ray was showed bibasal nodular lesions with a predominance of right hemithorax and reticular opacities in left apex. A new laryngoscopy revealed a mamelonated tumor in the arytenoid cartilage, which led to the initiation of the antituberculous treatment without confirming the diagnosis by biopsy, with clinical improvement and no serious sequelae at the end of treatment. The reason for presenting this case is to consider the possibility of tuberculosis in areas of high endemicity, in patients who have a laryngeal tumor of probable neoplastic etiology, and that a biopsy is not necessary for the diagnosis of laryngeal tuberculosis in cases associated with pulmonary symptomatology.
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spelling pubmed-63248512019-01-15 Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature Hurtado Alegre, Jorge Luis Trigoso Gutierrez, Anita Matos Prado, Eduardo Huaringa Marcelo, Jorge Cureus Internal Medicine Tuberculosis is the most frequent granulomatous disease but the involvement of the larynx is rare. Immunosuppressed patients have a higher risk of developing this clinical form due to primoinfection or reactivation of latent tuberculosis. It is common to confuse the diagnosis of laryngeal tuberculosis with laryngeal cancer because they have similar macroscopic lesions and both produce dysphonia of chronic evolution. We present the case of a pregnant woman with chronic dysphonia, dysphagia, and odynophagia, diagnosed initially with laryngeal cancer after the first laryngoscopy. However, the patient also presented with fever, productive cough, weight loss, and dyspnea. The sputum sample showed a positive result for acid-fast bacilli (AFB) test; chest X-ray was showed bibasal nodular lesions with a predominance of right hemithorax and reticular opacities in left apex. A new laryngoscopy revealed a mamelonated tumor in the arytenoid cartilage, which led to the initiation of the antituberculous treatment without confirming the diagnosis by biopsy, with clinical improvement and no serious sequelae at the end of treatment. The reason for presenting this case is to consider the possibility of tuberculosis in areas of high endemicity, in patients who have a laryngeal tumor of probable neoplastic etiology, and that a biopsy is not necessary for the diagnosis of laryngeal tuberculosis in cases associated with pulmonary symptomatology. Cureus 2018-11-05 /pmc/articles/PMC6324851/ /pubmed/30648077 http://dx.doi.org/10.7759/cureus.3545 Text en Copyright © 2018, Hurtado Alegre et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Hurtado Alegre, Jorge Luis
Trigoso Gutierrez, Anita
Matos Prado, Eduardo
Huaringa Marcelo, Jorge
Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature
title Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature
title_full Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature
title_fullStr Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature
title_full_unstemmed Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature
title_short Laryngeal Tuberculosis in Pregnant Women: A Case Report and Review of the Literature
title_sort laryngeal tuberculosis in pregnant women: a case report and review of the literature
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6324851/
https://www.ncbi.nlm.nih.gov/pubmed/30648077
http://dx.doi.org/10.7759/cureus.3545
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