Azole resistance of Malassezia pachydermatis causing treatment failure in a dog

A 5-year-old neutered female toy Poodle chronically treated with systemic and topical azoles to control recurrent Malassezia dermatitis/otitis was presented because of the loss of treatment efficacy. Minimum Inhibitory Concentrations (MICs) obtained in vitro for various azoles (especially itraconazo...

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Detalles Bibliográficos
Autores principales: Angileri, Martina, Pasquetti, Mario, De Lucia, Michela, Peano, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325069/
https://www.ncbi.nlm.nih.gov/pubmed/30662826
http://dx.doi.org/10.1016/j.mmcr.2018.12.004
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author Angileri, Martina
Pasquetti, Mario
De Lucia, Michela
Peano, Andrea
author_facet Angileri, Martina
Pasquetti, Mario
De Lucia, Michela
Peano, Andrea
author_sort Angileri, Martina
collection PubMed
description A 5-year-old neutered female toy Poodle chronically treated with systemic and topical azoles to control recurrent Malassezia dermatitis/otitis was presented because of the loss of treatment efficacy. Minimum Inhibitory Concentrations (MICs) obtained in vitro for various azoles (especially itraconazole and ketoconazole) against Malassezia strains isolated from the dog were increased by several-fold compared with MICs obtained for control isolates. These results reinforced the assumption based on clinical observation, i.e. the development of azole resistance
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spelling pubmed-63250692019-01-18 Azole resistance of Malassezia pachydermatis causing treatment failure in a dog Angileri, Martina Pasquetti, Mario De Lucia, Michela Peano, Andrea Med Mycol Case Rep Case Report A 5-year-old neutered female toy Poodle chronically treated with systemic and topical azoles to control recurrent Malassezia dermatitis/otitis was presented because of the loss of treatment efficacy. Minimum Inhibitory Concentrations (MICs) obtained in vitro for various azoles (especially itraconazole and ketoconazole) against Malassezia strains isolated from the dog were increased by several-fold compared with MICs obtained for control isolates. These results reinforced the assumption based on clinical observation, i.e. the development of azole resistance Elsevier 2018-12-21 /pmc/articles/PMC6325069/ /pubmed/30662826 http://dx.doi.org/10.1016/j.mmcr.2018.12.004 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Angileri, Martina
Pasquetti, Mario
De Lucia, Michela
Peano, Andrea
Azole resistance of Malassezia pachydermatis causing treatment failure in a dog
title Azole resistance of Malassezia pachydermatis causing treatment failure in a dog
title_full Azole resistance of Malassezia pachydermatis causing treatment failure in a dog
title_fullStr Azole resistance of Malassezia pachydermatis causing treatment failure in a dog
title_full_unstemmed Azole resistance of Malassezia pachydermatis causing treatment failure in a dog
title_short Azole resistance of Malassezia pachydermatis causing treatment failure in a dog
title_sort azole resistance of malassezia pachydermatis causing treatment failure in a dog
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325069/
https://www.ncbi.nlm.nih.gov/pubmed/30662826
http://dx.doi.org/10.1016/j.mmcr.2018.12.004
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