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Functional Analysis of an Inducible Promoter Driven by Activation Signals from a Chimeric Antigen Receptor

Adoptive transfer of T cells expressing a chimeric antigen receptor (CAR) is a promising cell-based anticancer therapy. Although clinical studies of this approach show therapeutic efficacy, additional genetic modification is necessary to enhance the efficacy and safety of CAR-T cells. For example, p...

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Detalles Bibliográficos
Autores principales:	Uchibori, Ryosuke, Teruya, Takeshi, Ido, Hiroyuki, Ohmine, Ken, Sehara, Yoshihide, Urabe, Masashi, Mizukami, Hiroaki, Mineno, Junichi, Ozawa, Keiya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Gene & Cell Therapy 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325072/ https://www.ncbi.nlm.nih.gov/pubmed/30662937 http://dx.doi.org/10.1016/j.omto.2018.11.003

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