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The cirrhotic liver is depleted of docosahexaenoic acid (DHA), a key modulator of NF-κB and TGFβ pathways in hepatic stellate cells
Liver cirrhosis results from chronic hepatic damage and is characterized by derangement of the organ architecture with increased liver fibrogenesis and defective hepatocellular function. It frequently evolves into progressive hepatic insufficiency associated with high mortality unless liver transpla...
Autores principales: | Enguita, Mónica, Razquin, Nerea, Pamplona, Reinald, Quiroga, Jorge, Prieto, Jesús, Fortes, Puri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325107/ https://www.ncbi.nlm.nih.gov/pubmed/30622239 http://dx.doi.org/10.1038/s41419-018-1243-0 |
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