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Promotion of homology-directed DNA repair by polyamines

Polyamines, often elevated in cancer cells, have been shown to promote cell growth and proliferation. Whether polyamines regulate other cell functions remains unclear. Here, we explore whether and how polyamines affect genome integrity. When DNA double-strand break (DSB) is induced in hair follicles...

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Detalles Bibliográficos
Autores principales: Lee, Chih-Ying, Su, Guan-Chin, Huang, Wen-Yen, Ko, Min-Yu, Yeh, Hsin-Yi, Chang, Geen-Dong, Lin, Sung-Jan, Chi, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325121/
https://www.ncbi.nlm.nih.gov/pubmed/30622262
http://dx.doi.org/10.1038/s41467-018-08011-1