Argonaute 2 drives miR-145-5p-dependent gene expression program in breast cancer cells

To perform their regulatory functions, microRNAs (miRNAs) must assemble with any of the four mammalian Argonaute (Ago) family of proteins, Ago1–4, into an effector complex known as the RNA-induced silencing complex (RISC). While the mature miRNA guides the RISC complex to its target mRNA, the Ago pr...

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Detalles Bibliográficos
Autores principales: Bellissimo, Teresa, Tito, Claudia, Ganci, Federica, Sacconi, Andrea, Masciarelli, Silvia, Di Martino, Giuseppe, Porta, Natale, Cirenza, Mirko, Sorci, Melissa, De Angelis, Luciana, Rosa, Paolo, Calogero, Antonella, Fatica, Alessandro, Petrozza, Vincenzo, Fontemaggi, Giulia, Blandino, Giovanni, Fazi, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325137/
https://www.ncbi.nlm.nih.gov/pubmed/30622242
http://dx.doi.org/10.1038/s41419-018-1267-5

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