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Central dogma rates and the trade-off between precision and economy in gene expression

Steady-state protein abundance is set by four rates: transcription, translation, mRNA decay and protein decay. A given protein abundance can be obtained from infinitely many combinations of these rates. This raises the question of whether the natural rates for each gene result from historical accide...

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Detalles Bibliográficos
Autores principales: Hausser, Jean, Mayo, Avi, Keren, Leeat, Alon, Uri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325141/
https://www.ncbi.nlm.nih.gov/pubmed/30622246
http://dx.doi.org/10.1038/s41467-018-07391-8

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