Comparative Metabolomics and Transcriptomics Reveal Multiple Pathways Associated with Polymyxin Killing in Pseudomonas aeruginosa

Polymyxins are a last-line therapy against multidrug-resistant Pseudomonas aeruginosa; however, resistance to polymyxins has been increasingly reported. Therefore, understanding the mechanisms of polymyxin activity and resistance is crucial for preserving their clinical usefulness. This study employ...

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Detalles Bibliográficos
Autores principales: Han, Mei-Ling, Zhu, Yan, Creek, Darren J., Lin, Yu-Wei, Gutu, Alina D., Hertzog, Paul, Purcell, Tony, Shen, Hsin-Hui, Moskowitz, Samuel M., Velkov, Tony, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325167/
https://www.ncbi.nlm.nih.gov/pubmed/30637340
http://dx.doi.org/10.1128/mSystems.00149-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325167/
https://www.ncbi.nlm.nih.gov/pubmed/30637340
http://dx.doi.org/10.1128/mSystems.00149-18

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