A Transcriptomics Approach To Unveiling the Mechanisms of In Vitro Evolution towards Fluconazole Resistance of a Candida glabrata Clinical Isolate

Candida glabrata is an emerging fungal pathogen. Its increased prevalence is associated with its ability to rapidly develop antifungal drug resistance, particularly to azoles. In order to unravel new molecular mechanisms behind azole resistance, a transcriptomics analysis of the evolution of a C. gl...

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Detalles Bibliográficos
Autores principales: Cavalheiro, Mafalda, Costa, Catarina, Silva-Dias, Ana, Miranda, Isabel M., Wang, Can, Pais, Pedro, Pinto, Sandra N., Mil-Homens, Dalila, Sato-Okamoto, Michiyo, Takahashi-Nakaguchi, Azusa, Silva, Raquel M., Mira, Nuno P., Fialho, Arsénio M., Chibana, Hiroji, Rodrigues, Acácio G., Butler, Geraldine, Teixeira, Miguel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Mechanisms of Resistance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325195/
https://www.ncbi.nlm.nih.gov/pubmed/30348666
http://dx.doi.org/10.1128/AAC.00995-18

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