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A Novel Actin Binding Drug with In Vivo Efficacy

Occidiofungin is produced by the soil bacterium Burkolderia contaminans MS14 and is structurally similar or identical to the burkholdines, xylocandins, and cepacidines. This study identified the primary cellular target of occidiofungin, which was determined to be actin. The modification of occidiofu...

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Detalles Bibliográficos
Autores principales:	Ravichandran, Akshaya, Geng, Mengxin, Hull, Kenneth G., Li, Jing, Romo, Daniel, Lu, Shi-En, Albee, Aaron, Nutter, Christopher, Gordon, Donna M., Ghannoum, Mahmoud A., Lockless, Steve W., Smith, Leif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Mechanisms of Action: Physiological Effects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325233/ https://www.ncbi.nlm.nih.gov/pubmed/30323040 http://dx.doi.org/10.1128/AAC.01585-18

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