Low Postseroconversion CD4(+) T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection

A positive correlation between virus evolutionary rate and disease progression has been shown for human immunodeficiency virus type 1 (HIV-1) infection. Much less is known about HIV-2, the second causative agent of AIDS. We analyzed 528 HIV-2 env V1-C3 sequences generated from longitudinal plasma sa...

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Detalles Bibliográficos
Autores principales: Palm, Angelica A., Lemey, Philippe, Jansson, Marianne, Månsson, Fredrik, Kvist, Anders, Szojka, Zsófia, Biague, Antonio, da Silva, Zacarias José, Rowland-Jones, Sarah L., Norrgren, Hans, Esbjörnsson, Joakim, Medstrand, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325243/
https://www.ncbi.nlm.nih.gov/pubmed/30622192
http://dx.doi.org/10.1128/mBio.01245-18

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