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Coordination between Prefrontal Cortex Clock Gene Expression and Corticosterone Contributes to Enhanced Conditioned Fear Extinction Recall
Post-traumatic stress disorder (PTSD) is associated with impaired conditioned fear extinction learning, a ventromedial prefrontal cortex (vmPFC)-dependent process. PTSD is also associated with dysregulation of vmPFC, circadian, and glucocorticoid hormone function. Rats have rhythmic clock gene expre...
Autores principales: | Woodruff, Elizabeth R., Chun, Lauren E., Hinds, Laura R., Varra, Nicholas M., Tirado, Daniel, Morton, Sarah J., McClung, Colleen A., Spencer, Robert L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325539/ https://www.ncbi.nlm.nih.gov/pubmed/30627637 http://dx.doi.org/10.1523/ENEURO.0455-18.2018 |
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