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Nociceptin/Orphanin-FQ Inhibits Gonadotropin-Releasing Hormone Neurons via G-Protein-Gated Inwardly Rectifying Potassium Channels

The pulsatile release of gonadotropin-releasing hormone (GnRH) is a key feature of the hypothalamic–pituitary–gonadal axis. Kisspeptin neurons in the arcuate nucleus (ARC) trigger GnRH neuronal activity, but how GnRH neurons return to baseline electrical activity is unknown. Nociceptin/orphanin-FQ (...

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Detalles Bibliográficos
Autores principales:	Constantin, Stephanie, Wray, Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Society for Neuroscience 2018
Materias:	New Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325553/ https://www.ncbi.nlm.nih.gov/pubmed/30627649 http://dx.doi.org/10.1523/ENEURO.0161-18.2018

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