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Cryo-EM insight into the structure of MTOR complex 1 and its interactions with Rheb and substrates
The mechanistic target of rapamycin (MTOR) is a giant protein kinase that, together with the accessory proteins Raptor and mLst8, forms a complex of over 1 MDa known as MTOR complex 1 (MTORC1). MTORC1, through its protein kinase activity, controls the accretion of cell mass through the regulation of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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F1000 Research Limited
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325617/ https://www.ncbi.nlm.nih.gov/pubmed/30647914 http://dx.doi.org/10.12688/f1000research.16109.1 |