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Do sputum or circulating blood samples reflect the pulmonary transcriptomic differences of COPD patients? A multi-tissue transcriptomic network META-analysis
BACKGROUND: Previous studies have identified lung, sputum or blood transcriptomic biomarkers associated with the severity of airflow limitation in COPD. Yet, it is not clear whether the lung pathobiology is mirrored by these surrogate tissues. The aim of this study was to explore this question. METH...
Autores principales: | Faner, Rosa, Morrow, Jarrett D., Casas-Recasens, Sandra, Cloonan, Suzanne M., Noell, Guillaume, López-Giraldo, Alejandra, Tal-Singer, Ruth, Miller, Bruce E., Silverman, Edwin K., Agustí, Alvar, Hersh, Craig P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325784/ https://www.ncbi.nlm.nih.gov/pubmed/30621695 http://dx.doi.org/10.1186/s12931-018-0965-y |
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