The novel exchange protein activated by cyclic AMP 1 (EPAC1) agonist, I942, regulates inflammatory gene expression in human umbilical vascular endothelial cells (HUVECs)

Exchange protein activated by cyclic AMP (EPAC1) suppresses multiple inflammatory actions in vascular endothelial cells (VECs), partly due to its ability to induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene, the protein product of which inhibits interleukin 6 (IL6) signalling...

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Detalles Bibliográficos
Autores principales: Wiejak, Jolanta, van Basten, Boy, Luchowska-Stańska, Urszula, Hamilton, Graham, Yarwood, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325792/
https://www.ncbi.nlm.nih.gov/pubmed/30414891
http://dx.doi.org/10.1016/j.bbamcr.2018.11.004

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