Randomised open label exploratory, safety and tolerability study with calmangafodipir in patients treated with the 12-h regimen of N-acetylcysteine for paracetamol overdose—the PP100–01 for Overdose of Paracetamol (POP) trial: study protocol for a randomised controlled trial

BACKGROUND: Paracetamol (acetaminophen) overdose (POD) is the commonest cause of acute liver failure in Europe and North America. Current treatment involves the use of the antidote N-acetylcysteine (NAC) in patients deemed at risk of liver damage. This regimen was introduced in the 1970s and has rem...

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Detalles Bibliográficos
Autor principal: Dear, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325794/
https://www.ncbi.nlm.nih.gov/pubmed/30621764
http://dx.doi.org/10.1186/s13063-018-3134-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6325794/
https://www.ncbi.nlm.nih.gov/pubmed/30621764
http://dx.doi.org/10.1186/s13063-018-3134-1

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